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A generalized least-squares framework for rare-variant analysis in family data
Rare variants may, in part, explain some of the hereditability missing in current genome-wide association studies. Many gene-based rare-variant analysis approaches proposed in recent years are aimed at population-based samples, although analysis strategies for family-based samples are clearly warran...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143681/ https://www.ncbi.nlm.nih.gov/pubmed/25519378 http://dx.doi.org/10.1186/1753-6561-8-S1-S28 |