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A generalized least-squares framework for rare-variant analysis in family data

Rare variants may, in part, explain some of the hereditability missing in current genome-wide association studies. Many gene-based rare-variant analysis approaches proposed in recent years are aimed at population-based samples, although analysis strategies for family-based samples are clearly warran...

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Detalles Bibliográficos
Autores principales: Li, Dalin, Rotter,, Jerome I, Guo, Xiuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143681/
https://www.ncbi.nlm.nih.gov/pubmed/25519378
http://dx.doi.org/10.1186/1753-6561-8-S1-S28