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Prediction of genetic contributions to complex traits using whole genome sequencing data

Although markers identified by genome-wide association studies have individually strong statistical significance, their performance in prediction remains limited. Our goal was to use animal breeding genomic prediction models to predict additive genetic contributions for systolic blood pressure (SBP)...

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Detalles Bibliográficos
Autores principales: Yao, Chen, Leng, Ning, Weigel, Kent A, Lee, Kristine E, Engelman, Corinne D, Meyers, Kristin J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143683/
https://www.ncbi.nlm.nih.gov/pubmed/25519339
http://dx.doi.org/10.1186/1753-6561-8-S1-S68