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A multi-level model for analyzing whole genome sequencing family data with longitudinal traits
Compared with microarray-based genotyping, next-generation whole genome sequencing (WGS) studies have the strength to provide greater information for the identification of rare variants, which likely account for a significant portion of missing heritability of common human diseases. In WGS, family-b...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143693/ https://www.ncbi.nlm.nih.gov/pubmed/25519414 http://dx.doi.org/10.1186/1753-6561-8-S1-S86 |