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A multi-level model for analyzing whole genome sequencing family data with longitudinal traits

Compared with microarray-based genotyping, next-generation whole genome sequencing (WGS) studies have the strength to provide greater information for the identification of rare variants, which likely account for a significant portion of missing heritability of common human diseases. In WGS, family-b...

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Detalles Bibliográficos
Autores principales: Chen, Taoye, Santawisook, Patchara, Wu, Zheyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143693/
https://www.ncbi.nlm.nih.gov/pubmed/25519414
http://dx.doi.org/10.1186/1753-6561-8-S1-S86

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