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Penalized multivariate linear mixed model for longitudinal genome-wide association studies
We consider analysis of Genetic Analysis Workshop 18 data, which involves multiple longitudinal traits and dense genome-wide single-nucleotide polymorphism (SNP) markers. We use a multivariate linear mixed model to account for the covariance of random effects and multivariate residuals. We divide th...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143695/ https://www.ncbi.nlm.nih.gov/pubmed/25519343 http://dx.doi.org/10.1186/1753-6561-8-S1-S73 |