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Family-based Bayesian collapsing method for rare-variant association study

In this study, we analyze the Genetic Analysis Workshop 18 data to identify the genes and underlying single-nucleotide polymorphisms on 11 chromosomes that exhibit significant association with systolic blood pressure. We propose a novel family-based method for rare-variant association detection base...

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Detalles Bibliográficos
Autores principales: He, Liang, Pitkäniemi, Janne M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143697/
https://www.ncbi.nlm.nih.gov/pubmed/25519322
http://dx.doi.org/10.1186/1753-6561-8-S1-S37