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An exploration of heterogeneity in genetic analysis of complex pedigrees: linkage and association using whole genome sequencing data in the MAP4 region

We conduct pedigree-based linkage and association analyses of simulated systolic blood pressure data in the nonascertained large Mexican American pedigrees provided by Genetic Analysis Workshop 18, focusing on observed sequence variants in MAP4 on chromosome 3. Because pedigrees are large and sequen...

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Detalles Bibliográficos
Autores principales: Bull, Shelley B, Chen, Zhijian, Tan, Kuan-Rui, Poirier, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143705/
https://www.ncbi.nlm.nih.gov/pubmed/25519361
http://dx.doi.org/10.1186/1753-6561-8-S1-S107