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A comparison of whole genome sequencing with exome sequencing for family-based association studies

As the cost of DNA sequencing decreases, association studies based on whole genome sequencing are now becoming feasible. It is still unclear, however, how much more we could gain from whole genome sequencing compared to exome sequencing, which has been widely used to study a variety of diseases. In...

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Detalles Bibliográficos
Autores principales: Lacey, Sean, Chung, Jae Yoon, Lin, Honghuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143706/
https://www.ncbi.nlm.nih.gov/pubmed/25519383
http://dx.doi.org/10.1186/1753-6561-8-S1-S38