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Detecting longitudinal effects of haplotypes and smoking on hypertension using B-splines and Bayesian LASSO
The behavior of a gene can be dynamic; thus, if longitudinal data are available, it is important that we study the dynamic effects of genes on a trait over time. The effect of a haplotype can be expressed by time-varying coefficients. In this paper, we use the natural cubic B-spline to express these...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143712/ https://www.ncbi.nlm.nih.gov/pubmed/25519413 http://dx.doi.org/10.1186/1753-6561-8-S1-S85 |