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Detecting association of rare and common variants by testing an optimally weighted combination of variants with longitudinal data
Increasing evidence shows that complex diseases are caused by both common and rare variants. Recently, several statistical methods for detecting associations of rare variants have been developed, including the test for testing the effect of an optimally weighted combination of variants (TOW) develop...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143720/ https://www.ncbi.nlm.nih.gov/pubmed/25519418 http://dx.doi.org/10.1186/1753-6561-8-S1-S91 |