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Two-stage family-based designs for sequencing studies

The cost of next-generation sequencing is now approaching that of the first generation of genome-wide single-nucleotide genotyping panels, but this is still out of reach for large-scale epidemiologic studies with tens of thousands of subjects. Furthermore, the anticipated yield of millions of rare v...

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Detalles Bibliográficos
Autores principales: Yang, Zhao, Thomas, Duncan C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143728/
https://www.ncbi.nlm.nih.gov/pubmed/25519319
http://dx.doi.org/10.1186/1753-6561-8-S1-S32