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Identifying rare variant associations in population-based and family-based designs

For almost all complex traits studied in humans, the identified genetic variants discovered to date have accounted for only a small portion of the estimated trait heritability. Consequently, several methods have been developed to identify rare single-nucleotide variants associated with complex trait...

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Detalles Bibliográficos
Autores principales: Turkmen, Asuman S, Lin, Shili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143803/
https://www.ncbi.nlm.nih.gov/pubmed/25519393
http://dx.doi.org/10.1186/1753-6561-8-S1-S58