Cargando…
Identifying rare variant associations in population-based and family-based designs
For almost all complex traits studied in humans, the identified genetic variants discovered to date have accounted for only a small portion of the estimated trait heritability. Consequently, several methods have been developed to identify rare single-nucleotide variants associated with complex trait...
Autores principales: | Turkmen, Asuman S, Lin, Shili |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143803/ https://www.ncbi.nlm.nih.gov/pubmed/25519393 http://dx.doi.org/10.1186/1753-6561-8-S1-S58 |
Ejemplares similares
-
Gene-based partial least-squares approaches for detecting rare variant associations with complex traits
por: Turkmen, Asuman S, et al.
Publicado: (2011) -
Blocking Approach for Identification of Rare Variants in Family-Based Association Studies
por: Turkmen, Asuman S., et al.
Publicado: (2014) -
Family- and population-based designs identify different rare causal variants
por: Zhang, Xue, et al.
Publicado: (2011) -
Family-based tests applied to extended pedigrees identify rare variants related to hypertension
por: Xu, Mengyuan, et al.
Publicado: (2014) -
Application of family-based tests of association for rare variants to pathways
por: Greco, Brian, et al.
Publicado: (2014)