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Considering interactive effects in the identification of influential regions with extremely rare variants via fixed bin approach

In this study, we analyze the Genetic Analysis Workshop 18 (GAW18) data to identify regions of single-nucleotide polymorphisms (SNPs), which significantly influence hypertension status among individuals. We have studied the marginal impact of these regions on disease status in the past, but we exten...

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Detalles Bibliográficos
Autores principales: Agne, Michael, Huang, Chien-Hsun, Hu, Inchi, Wang, Haitian, Zheng, Tian, Lo, Shaw-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143804/
https://www.ncbi.nlm.nih.gov/pubmed/25519400
http://dx.doi.org/10.1186/1753-6561-8-S1-S7