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Pro-oxidant activity of indicaxanthin from Opuntia ficus indica modulates arachidonate metabolism and prostaglandin synthesis through lipid peroxide production in LPS-stimulated RAW 264.7 macrophages

Macrophages come across active prostaglandin (PG) metabolism during inflammation, shunting early production of pro-inflammatory towards anti-inflammatory mediators terminating the process. This work for the first time provides evidence that a phytochemical may modulate the arachidonate (AA) metaboli...

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Detalles Bibliográficos
Autores principales: Allegra, M., D’Acquisto, F., Tesoriere, L., Attanzio, A., Livrea, M.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143813/
https://www.ncbi.nlm.nih.gov/pubmed/25180166
http://dx.doi.org/10.1016/j.redox.2014.07.004