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Neutral sphingomyelinase-3 mediates TNF-stimulated oxidant activity in skeletal muscle

AIMS: Sphingolipid and oxidant signaling affect glucose uptake, atrophy, and force production of skeletal muscle similarly and both are stimulated by tumor necrosis factor (TNF), suggesting a connection between systems. Sphingolipid signaling is initiated by neutral sphingomyelinase (nSMase), a fami...

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Detalles Bibliográficos
Autores principales: Moylan, Jennifer S., Smith, Jeffrey D., Wolf Horrell, Erin M., McLean, Julie B., Deevska, Gergana M., Bonnell, Mark R., Nikolova-Karakashian, Mariana N., Reid, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143815/
https://www.ncbi.nlm.nih.gov/pubmed/25180167
http://dx.doi.org/10.1016/j.redox.2014.07.006