Adjustment of familial relatedness in association test for rare variants

High-throughput sequencing technology allows researchers to test associations between phenotypes and all the variants identified throughout the genome, and is especially useful for analyzing rare variants. However, the statistical power to identify phenotype-associated rare variants is very low with...

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Detalles Bibliográficos
Autores principales: Li, Cong, Yang, Can, Chen, Mengjie, Chen, Xiaowei, Hou, Lin, Zhao, Hongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143885/
https://www.ncbi.nlm.nih.gov/pubmed/25519384
http://dx.doi.org/10.1186/1753-6561-8-S1-S39

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143885/
https://www.ncbi.nlm.nih.gov/pubmed/25519384
http://dx.doi.org/10.1186/1753-6561-8-S1-S39

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