RasGRP3 limits Toll-like receptor-triggered inflammatory response in macrophages by activating Rap1 small GTPase

Host immune cells can detect and destruct invading pathogens via pattern-recognition receptors. Small Rap GTPases act as conserved molecular switches coupling extracellular signals to various cellular responses, but their roles as regulators in Toll-like receptor (TLR) signalling have not been fully...

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Detalles Bibliográficos
Autores principales: Tang, Songqing, Chen, Taoyong, Yu, Zhou, Zhu, Xuhui, Yang, Mingjin, Xie, Bin, Li, Nan, Cao, Xuetao, Wang, Jianli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143924/
https://www.ncbi.nlm.nih.gov/pubmed/25118589
http://dx.doi.org/10.1038/ncomms5657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143924/
https://www.ncbi.nlm.nih.gov/pubmed/25118589
http://dx.doi.org/10.1038/ncomms5657

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