Strong effects of genetic and lifestyle factors on biomarker variation and use of personalized cutoffs

Ideal biomarkers used for disease diagnosis should display deviating levels in affected individuals only and be robust to factors unrelated to the disease. Here we show the impact of genetic, clinical and lifestyle factors on circulating levels of 92 protein biomarkers for cancer and inflammation, u...

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Detalles Bibliográficos
Autores principales: Enroth, Stefan, Johansson, Åsa, Enroth, Sofia Bosdotter, Gyllensten, Ulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143927/
https://www.ncbi.nlm.nih.gov/pubmed/25147954
http://dx.doi.org/10.1038/ncomms5684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143927/
https://www.ncbi.nlm.nih.gov/pubmed/25147954
http://dx.doi.org/10.1038/ncomms5684

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