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Identification of a human neonatal immune-metabolic network associated with bacterial infection

Understanding how human neonates respond to infection remains incomplete. Here, a system-level investigation of neonatal systemic responses to infection shows a surprisingly strong but unbalanced homeostatic immune response; developing an elevated set-point of myeloid regulatory signalling and sugar...

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Detalles Bibliográficos
Autores principales: Smith, Claire L., Dickinson, Paul, Forster, Thorsten, Craigon, Marie, Ross, Alan, Khondoker, Mizanur R., France, Rebecca, Ivens, Alasdair, Lynn, David J., Orme, Judith, Jackson, Allan, Lacaze, Paul, Flanagan, Katie L., Stenson, Benjamin J., Ghazal, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143936/
https://www.ncbi.nlm.nih.gov/pubmed/25120092
http://dx.doi.org/10.1038/ncomms5649