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Variable escape from X-chromosome inactivation: Identifying factors that tip the scales towards expression

In humans over 15% of X-linked genes have been shown to ‘escape’ from X-chromosome inactivation (XCI): they continue to be expressed to some extent from the inactive X chromosome. Mono-allelic expression is anticipated within a cell for genes subject to XCI, but random XCI usually results in express...

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Detalles Bibliográficos
Autores principales: Peeters, Samantha B, Cotton, Allison M, Brown, Carolyn J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143967/
https://www.ncbi.nlm.nih.gov/pubmed/24913292
http://dx.doi.org/10.1002/bies.201400032