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Mechanisms underlying differential response to estrogen-induced apoptosis in long-term estrogen-deprived breast cancer cells

Models of long-term estrogen-deprived breast cancer cells are utilized in the laboratory to mimic clinical aromatase inhibitor-resistant breast cancer and serve as a tool to discover new therapeutic strategies. The MCF-7:5C and MCF-7:2A subclones were generated through long-term estrogen deprivation...

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Detalles Bibliográficos
Autores principales: SWEENEY, ELIZABETH E., FAN, PING, JORDAN, V. CRAIG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144033/
https://www.ncbi.nlm.nih.gov/pubmed/24604139
http://dx.doi.org/10.3892/ijo.2014.2329