Ticlopidine in Its Prodrug Form Is a Selective Inhibitor of Human NTPDase1

Nucleoside triphosphate diphosphohydrolase-1 (NTPDase1), like other ectonucleotidases, controls extracellular nucleotide levels and consequently their (patho)physiological responses such as in thrombosis, inflammation, and cancer. Selective NTPDase1 inhibitors would therefore be very useful. We prev...

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Detalles Bibliográficos
Autores principales: Lecka, Joanna, Fausther, Michel, Künzli, Beat, Sévigny, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144158/
https://www.ncbi.nlm.nih.gov/pubmed/25180024
http://dx.doi.org/10.1155/2014/547480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144158/
https://www.ncbi.nlm.nih.gov/pubmed/25180024
http://dx.doi.org/10.1155/2014/547480

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