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Ticlopidine in Its Prodrug Form Is a Selective Inhibitor of Human NTPDase1
Nucleoside triphosphate diphosphohydrolase-1 (NTPDase1), like other ectonucleotidases, controls extracellular nucleotide levels and consequently their (patho)physiological responses such as in thrombosis, inflammation, and cancer. Selective NTPDase1 inhibitors would therefore be very useful. We prev...
Autores principales: | Lecka, Joanna, Fausther, Michel, Künzli, Beat, Sévigny, Jean |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144158/ https://www.ncbi.nlm.nih.gov/pubmed/25180024 http://dx.doi.org/10.1155/2014/547480 |
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