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Suppression of APOBEC3-mediated restriction of HIV-1 by Vif

The APOBEC3 restriction factors are a family of deoxycytidine deaminases that are able to suppress replication of viruses with a single-stranded DNA intermediate by inducing mutagenesis and functional inactivation of the virus. Of the seven human APOBEC3 enzymes, only APOBEC3-D, -F, -G, and -H appea...

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Detalles Bibliográficos
Autores principales: Feng, Yuqing, Baig, Tayyba T., Love, Robin P., Chelico, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144255/
https://www.ncbi.nlm.nih.gov/pubmed/25206352
http://dx.doi.org/10.3389/fmicb.2014.00450