Hierarchical linear modeling of longitudinal pedigree data for genetic association analysis

Genetic association analysis on complex phenotypes under a longitudinal design involving pedigrees encounters the problem of correlation within pedigrees, which could affect statistical assessment of the genetic effects. Approaches have been proposed to integrate kinship correlation into the mixed-e...

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Detalles Bibliográficos
Autores principales: Tan, Qihua, B Hjelmborg, Jacob V, Thomassen, Mads, Jensen, Andreas Kryger, Christiansen, Lene, Christensen, Kaare, Zhao, Jing Hua, Kruse, Torben A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144324/
https://www.ncbi.nlm.nih.gov/pubmed/25519411
http://dx.doi.org/10.1186/1753-6561-8-S1-S82

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144324/
https://www.ncbi.nlm.nih.gov/pubmed/25519411
http://dx.doi.org/10.1186/1753-6561-8-S1-S82

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