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Hierarchical linear modeling of longitudinal pedigree data for genetic association analysis
Genetic association analysis on complex phenotypes under a longitudinal design involving pedigrees encounters the problem of correlation within pedigrees, which could affect statistical assessment of the genetic effects. Approaches have been proposed to integrate kinship correlation into the mixed-e...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144324/ https://www.ncbi.nlm.nih.gov/pubmed/25519411 http://dx.doi.org/10.1186/1753-6561-8-S1-S82 |