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The Drosophila F-box protein Fbxl7 binds to the protocadherin Fat and regulates Dachs localization and Hippo signaling

The Drosophila protocadherin Fat (Ft) regulates growth, planar cell polarity (PCP) and proximodistal patterning. A key downstream component of Ft signaling is the atypical myosin Dachs (D). Multiple regions of the intracellular domain of Ft have been implicated in regulating growth and PCP but how F...

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Detalles Bibliográficos
Autores principales: Bosch, Justin A, Sumabat, Taryn M, Hafezi, Yassi, Pellock, Brett J, Gandhi, Kevin D, Hariharan, Iswar K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144329/
https://www.ncbi.nlm.nih.gov/pubmed/25107277
http://dx.doi.org/10.7554/eLife.03383