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Creatine transporter (SLC6A8) knockout mice display an increased capacity for in vitro creatine biosynthesis in skeletal muscle

The present study aimed to investigate whether skeletal muscle from whole body creatine transporter (CrT; SLC6A8) knockout mice (CrT(-/y)) actually contained creatine (Cr) and if so, whether this Cr could result from an up regulation of muscle Cr biosynthesis. Gastrocnemius muscle from CrT(-/y) and...

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Detalles Bibliográficos
Autores principales: Russell, Aaron P., Ghobrial, Lobna, Wright, Craig R., Lamon, Séverine, Brown, Erin L., Kon, Michihiro, Skelton, Matthew R., Snow, Rodney J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144344/
https://www.ncbi.nlm.nih.gov/pubmed/25206338
http://dx.doi.org/10.3389/fphys.2014.00314