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Expression of selected pathway-marker genes in human urothelial cells exposed chronically to a non-cytotoxic concentration of monomethylarsonous acid

Bladder cancer has been associated with chronic arsenic exposure. Monomethylarsonous acid [MMA(III)] is a metabolite of inorganic arsenic and has been shown to transform an immortalized urothelial cell line (UROtsa) at concentrations 20-fold less than arsenite. MMA(III) was used as a model arsenical...

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Detalles Bibliográficos
Autores principales: Medeiros, Matthew, Le, Tam Minh, Troup, Daniel, Novak, Petr, Gandolfi, A. Jay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144464/
https://www.ncbi.nlm.nih.gov/pubmed/25177542
http://dx.doi.org/10.1016/j.toxrep.2014.07.004