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Pathway analysis for genetic association studies: to do, or not to do? That is the question

In Genetic Analysis Workshop 18 data, we used a 3-stage approach to explore the benefits of pathway analysis in improving a model to predict 2 diastolic blood pressure phenotypes as a function of genetic variation. At stage 1, gene-based tests of association in family data of approximately 800 indiv...

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Detalles Bibliográficos
Autores principales: Dufresne, Line, Oualkacha, Karim, Forgetta, Vincenzo, Greenwood, Celia MT
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144468/
https://www.ncbi.nlm.nih.gov/pubmed/25519357
http://dx.doi.org/10.1186/1753-6561-8-S1-S103