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Neuroinflammation and neurologic deficits in diabetes linked to brain accumulation of amylin
BACKGROUND: We recently found that brain tissue from patients with type-2 diabetes (T2D) and cognitive impairment contains deposits of amylin, an amyloidogenic hormone synthesized and co-secreted with insulin by pancreatic β-cells. Amylin deposition is promoted by chronic hypersecretion of amylin (h...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144699/ https://www.ncbi.nlm.nih.gov/pubmed/25149184 http://dx.doi.org/10.1186/1750-1326-9-30 |