Coupling of Transmembrane Helix Orientation To Membrane Release of the Juxtamembrane Region in FGFR3

[Image: see text] Activation of the protein tyrosine kinase receptors requires the coupling of ligand binding to a change in both the proximity and orientation of the single transmembrane (TM) helices of receptor monomers to allow transphosphorylation of the receptor kinase domain. We make use of pe...

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Detalles Bibliográficos
Autores principales: Tamagaki, Hiroko, Furukawa, Yusuke, Yamaguchi, Ritsuko, Hojo, Hironobu, Aimoto, Saburo, Smith, Steven O., Sato, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144707/
https://www.ncbi.nlm.nih.gov/pubmed/25010350
http://dx.doi.org/10.1021/bi500327q

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144707/
https://www.ncbi.nlm.nih.gov/pubmed/25010350
http://dx.doi.org/10.1021/bi500327q

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