Effective Protein Separation by Coupling Hydrophobic Interaction and Reverse Phase Chromatography for Top-down Proteomics

[Image: see text] One of the challenges in proteomics is the proteome’s complexity, which necessitates the fractionation of proteins prior to the mass spectrometry (MS) analysis. Despite recent advances in top-down proteomics, separation of intact proteins remains challenging. Hydrophobic interactio...

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Detalles Bibliográficos
Autores principales: Xiu, Lichen, Valeja, Santosh G., Alpert, Andrew J., Jin, Song, Ge, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144745/
https://www.ncbi.nlm.nih.gov/pubmed/24968279
http://dx.doi.org/10.1021/ac501836k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144745/
https://www.ncbi.nlm.nih.gov/pubmed/24968279
http://dx.doi.org/10.1021/ac501836k

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