Approach to Characterization of the Higher Order Structure of Disulfide-Containing Proteins Using Hydrogen/Deuterium Exchange and Top-Down Mass Spectrometry

[Image: see text] Top-down hydrogen/deuterium exchange (HDX) with mass spectrometric (MS) detection has recently matured to become a potent biophysical tool capable of providing valuable information on higher order structure and conformational dynamics of proteins at an unprecedented level of struct...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Guanbo, Kaltashov, Igor A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144750/
https://www.ncbi.nlm.nih.gov/pubmed/24988145
http://dx.doi.org/10.1021/ac501789e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144750/
https://www.ncbi.nlm.nih.gov/pubmed/24988145
http://dx.doi.org/10.1021/ac501789e

Ejemplares similares