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Combinational Delivery of Hydrophobic and Hydrophilic Anticancer Drugs in Single Nanoemulsions To Treat MDR in Cancer

[Image: see text] In this study, we developed the core-matched nanoemulsions (NEs) functionalized by vitamin E (VE) and tocopherol poly(ethylene glycol)succinate (TPGS) to codeliver hydrophobic and hydrophilic drugs, paclitaxel (PTX) and 5-fluoroucacil (5-FU), in order to achieve synergistic effects...

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Detalles Bibliográficos
Autores principales: Ma, Yan, Liu, Dan, Wang, Dun, Wang, Yongjun, Fu, Qiang, Fallon, John K., Yang, Xinggang, He, Zhonggui, Liu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144753/
https://www.ncbi.nlm.nih.gov/pubmed/24712391
http://dx.doi.org/10.1021/mp400778r