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Evaluation of (99m)Tc-Probestin SPECT As a Novel Technique for Noninvasive Imaging of Kidney Aminopeptidase N Expression

[Image: see text] Aminopeptidase N (APN; CD13; EC 3.4.11.2) is a zinc-dependent membrane-bound exopeptidase that catalyzes the removal of N-terminal amino acids from peptides. APN is known to be highly expressed on renal cortical proximal tubules. APN expression levels are markedly decreased under t...

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Detalles Bibliográficos
Autores principales: Pathuri, Gopal, Madka, Venkateshwar, Hedrick, Andria F., Lightfoot, Stanley A., Awasthi, Vibhudutta, Cowley, Benjamin D., Rao, Chinthalapally V., Gali, Hariprasad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144757/
https://www.ncbi.nlm.nih.gov/pubmed/24988047
http://dx.doi.org/10.1021/mp5002872