[6]-Gingerol Induces Caspase-Dependent Apoptosis and Prevents PMA-Induced Proliferation in Colon Cancer Cells by Inhibiting MAPK/AP-1 Signaling

We report mechanism-based evidence for the anticancer and chemopreventive efficacy of [6]-gingerol, the major active principle of the medicinal plant, Ginger (Zingiber officinale), in colon cancer cells. The compound was evaluated in two human colon cancer cell lines for its cytotoxic effect and the...

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Detalles Bibliográficos
Autores principales: Radhakrishnan, EK, Bava, Smitha V., Narayanan, Sai Shyam, Nath, Lekshmi R., Thulasidasan, Arun Kumar T., Soniya, Eppurathu Vasudevan, Anto, Ruby John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144808/
https://www.ncbi.nlm.nih.gov/pubmed/25157570
http://dx.doi.org/10.1371/journal.pone.0104401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144808/
https://www.ncbi.nlm.nih.gov/pubmed/25157570
http://dx.doi.org/10.1371/journal.pone.0104401

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