Enzymatic Oxidation of Cholesterol: Properties and Functional Effects of Cholestenone in Cell Membranes

Bacterial cholesterol oxidase is commonly used as an experimental tool to reduce cellular cholesterol content. That the treatment also generates the poorly degradable metabolite 4-cholesten-3-one (cholestenone) has received less attention. Here, we investigated the membrane partitioning of cholesten...

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Detalles Bibliográficos
Autores principales: Neuvonen, Maarit, Manna, Moutusi, Mokkila, Sini, Javanainen, Matti, Rog, Tomasz, Liu, Zheng, Bittman, Robert, Vattulainen, Ilpo, Ikonen, Elina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144813/
https://www.ncbi.nlm.nih.gov/pubmed/25157633
http://dx.doi.org/10.1371/journal.pone.0103743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144813/
https://www.ncbi.nlm.nih.gov/pubmed/25157633
http://dx.doi.org/10.1371/journal.pone.0103743

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