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Enzymatic Oxidation of Cholesterol: Properties and Functional Effects of Cholestenone in Cell Membranes
Bacterial cholesterol oxidase is commonly used as an experimental tool to reduce cellular cholesterol content. That the treatment also generates the poorly degradable metabolite 4-cholesten-3-one (cholestenone) has received less attention. Here, we investigated the membrane partitioning of cholesten...
Autores principales: | Neuvonen, Maarit, Manna, Moutusi, Mokkila, Sini, Javanainen, Matti, Rog, Tomasz, Liu, Zheng, Bittman, Robert, Vattulainen, Ilpo, Ikonen, Elina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144813/ https://www.ncbi.nlm.nih.gov/pubmed/25157633 http://dx.doi.org/10.1371/journal.pone.0103743 |
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