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Tumour Microenvironments Induce Expression of Urokinase Plasminogen Activator Receptor (uPAR) and Concomitant Activation of Gelatinolytic Enzymes

BACKGROUND: The urokinase plasminogen activator receptor (uPAR) is associated with poor prognosis in oral squamous cell carcinoma (OSCC), and increased expression of uPAR is often found at the invasive tumour front. The aim of the current study was to elucidate the role of uPAR in invasion and metas...

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Detalles Bibliográficos
Autores principales: Magnussen, Synnøve, Hadler-Olsen, Elin, Latysheva, Nadezhda, Pirila, Emma, Steigen, Sonja E., Hanes, Robert, Salo, Tuula, Winberg, Jan-Olof, Uhlin-Hansen, Lars, Svineng, Gunbjørg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144900/
https://www.ncbi.nlm.nih.gov/pubmed/25157856
http://dx.doi.org/10.1371/journal.pone.0105929