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Tumour Microenvironments Induce Expression of Urokinase Plasminogen Activator Receptor (uPAR) and Concomitant Activation of Gelatinolytic Enzymes
BACKGROUND: The urokinase plasminogen activator receptor (uPAR) is associated with poor prognosis in oral squamous cell carcinoma (OSCC), and increased expression of uPAR is often found at the invasive tumour front. The aim of the current study was to elucidate the role of uPAR in invasion and metas...
Autores principales: | Magnussen, Synnøve, Hadler-Olsen, Elin, Latysheva, Nadezhda, Pirila, Emma, Steigen, Sonja E., Hanes, Robert, Salo, Tuula, Winberg, Jan-Olof, Uhlin-Hansen, Lars, Svineng, Gunbjørg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144900/ https://www.ncbi.nlm.nih.gov/pubmed/25157856 http://dx.doi.org/10.1371/journal.pone.0105929 |
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