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Acute lipopolysaccharide exposure facilitates epileptiform activity via enhanced excitatory synaptic transmission and neuronal excitability in vitro

Growing evidence indicates brain inflammation has been involved in the genesis of seizures. However, the direct effect of acute inflammation on neuronal circuits is not well known. Lipopolysaccharide (LPS) has been used extensively to stimulate brain inflammatory responses both in vivo and in vitro....

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Detalles Bibliográficos
Autores principales: Gao, Fei, Liu, Zhiqiang, Ren, Wei, Jiang, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144925/
https://www.ncbi.nlm.nih.gov/pubmed/25170268
http://dx.doi.org/10.2147/NDT.S65695