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Chemical shift assignment of the ataxin-1 AXH domain in complex with a CIC ligand peptide

Ataxin-1 is the protein responsible for the genetically-inherited neurodegenerative disease spinocerebellar ataxia type-1 linked to the expansion of a polyglutamine tract within the protein sequence. The AXH domain of ataxin-1 is essential for the protein to function as a transcriptional co-represso...

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Detalles Bibliográficos
Autores principales: de Chiara, Cesira, Kelly, Geoff, Menon, Rajesh P., McCormick, John, Pastore, Annalisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145211/
https://www.ncbi.nlm.nih.gov/pubmed/23853075
http://dx.doi.org/10.1007/s12104-013-9509-z