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Chemical shift assignment of the ataxin-1 AXH domain in complex with a CIC ligand peptide
Ataxin-1 is the protein responsible for the genetically-inherited neurodegenerative disease spinocerebellar ataxia type-1 linked to the expansion of a polyglutamine tract within the protein sequence. The AXH domain of ataxin-1 is essential for the protein to function as a transcriptional co-represso...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145211/ https://www.ncbi.nlm.nih.gov/pubmed/23853075 http://dx.doi.org/10.1007/s12104-013-9509-z |