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Critical limitations of consensus clustering in class discovery

Consensus clustering (CC) has been adopted for unsupervised class discovery in many genomic studies. It calculates how frequently two samples are grouped together in repeated clustering runs, and uses the resulting pairwise "consensus rates" for visual demonstration that clusters exist, fo...

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Detalles Bibliográficos
Autores principales: Șenbabaoğlu, Yasin, Michailidis, George, Li, Jun Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145288/
https://www.ncbi.nlm.nih.gov/pubmed/25158761
http://dx.doi.org/10.1038/srep06207