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A Medium-Chain Fatty Acid, Capric Acid, Inhibits RANKL-Induced Osteoclast Differentiation via the Suppression of NF-κB Signaling and Blocks Cytoskeletal Organization and Survival in Mature Osteoclasts

Fatty acids, important components of a normal diet, have been reported to play a role in bone metabolism. Osteoclasts are bone-resorbing cells that are responsible for many bone-destructive diseases such as osteoporosis. In this study, we investigated the impact of a medium-chain fatty acid, capric...

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Detalles Bibliográficos
Autores principales: Kim, Hyun-Ju, Yoon, Hye-Jin, Kim, Shin-Yoon, Yoon, Young-Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145371/
https://www.ncbi.nlm.nih.gov/pubmed/25134536
http://dx.doi.org/10.14348/molcells.2014.0153