TAp73 and ΔNp73 Have Opposing Roles in 5-aza-2′-Deoxycytidine-Induced Apoptosis in Breast Cancer Cells

The p73 gene contains an extrinsic P1 promoter and an intrinsic P2 promoter, controlling the transcription of the pro-apoptotic TAp73 isoform and the anti-apoptotic ΔΝp73 isoform, respectively. The DNA methylation status of both promoters act equally in the epigenetic transcriptional regulation of t...

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Detalles Bibliográficos
Autores principales: Lai, Jing, Yang, Fang, Zhang, Wenwen, Wang, Yanru, Xu, Jing, Song, Wei, Huang, Guichun, Gu, Jun, Guan, Xiaoxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145372/
https://www.ncbi.nlm.nih.gov/pubmed/25134538
http://dx.doi.org/10.14348/molcells.2014.0154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145372/
https://www.ncbi.nlm.nih.gov/pubmed/25134538
http://dx.doi.org/10.14348/molcells.2014.0154

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