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E-Cadherin and Gastric Cancer: Cause, Consequence, and Applications

E-cadherin (epithelial-cadherin), encoded by the CDH1 gene, is a transmembrane glycoprotein playing a crucial role in maintaining cell-cell adhesion. E-cadherin has been reported to be a tumor suppressor and to be down regulated in gastric cancer. Besides genetic mutations in CDH1 gene to induce her...

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Detalles Bibliográficos
Autores principales: Liu, Xin, Chu, Kent-Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145387/
https://www.ncbi.nlm.nih.gov/pubmed/25184143
http://dx.doi.org/10.1155/2014/637308