Higher criticism approach to detect rare variants using whole genome sequencing data

Because of low statistical power of single-variant tests for whole genome sequencing (WGS) data, the association test for variant groups is a key approach for genetic mapping. To address the features of sparse and weak genetic effects to be detected, the higher criticism (HC) approach has been propo...

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Detalles Bibliográficos
Autores principales: Xuan, Jing, Yang, Li, Wu, Zheyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145405/
https://www.ncbi.nlm.nih.gov/pubmed/25519367
http://dx.doi.org/10.1186/1753-6561-8-S1-S14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145405/
https://www.ncbi.nlm.nih.gov/pubmed/25519367
http://dx.doi.org/10.1186/1753-6561-8-S1-S14

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